Last edited by Grolkis
Thursday, July 23, 2020 | History

6 edition of High throughput screening found in the catalog.

High throughput screening

methods and protocols

  • 228 Want to read
  • 8 Currently reading

Published by Humana Press in Totowa, N.J .
Written in English

    Subjects:
  • High throughput screening (Drug development),
  • Pharmaceutical chemistry -- Methods

  • Edition Notes

    Includes bibliographical references and index

    Statementedited by William P. Janzen
    SeriesMethods in molecular biology -- 190, Methods in Molecular Biology (Clifton, N.J.) -- 190
    ContributionsJanzen, William P
    Classifications
    LC ClassificationsRS419.5 .H54 2002
    The Physical Object
    Paginationix, 265 p. :
    Number of Pages265
    ID Numbers
    Open LibraryOL18136318M
    ISBN 100896038890
    LC Control Number2001039417

    Get this from a library! High-throughput screening assays in toxicology. [Hao Zhu, (Chemist); Menghang Xia;] -- "This book focuses on recently developed High-Throughput Screening (HTS) assay protocols, many involved in the ToxCast and/or Tox21 initiatives, and the relevant HTS data analysis techniques. Divided. High throughput flow cytometry for multifactorial evaluation of novel therapeutic IntelliCyt’s iQue Screener PLUS platform is a high throughput suspension cell screening platform that facilitates simultaneous assessment of multiple parameters such as cell health and function from multiple cell types in a single well, while using minimal.

    This book summarizes the latest research and applications of sensor technologies for online and high throughput screening of food. The book first introduces high throughput screening strategies and technology platforms, and discusses key issues in sample collection and preparation. High throughput screening (HTS) is a drug discovery technique employed for screening and evaluation of large number of biological modulators and effectors against selected target. Over last two decade, high throughput screening has gained a widespread popularity and has become a standard method of drug discovery in the pharmaceutical industry.

    ISBN: OCLC Number: Description: xii, pages: illustrations ; 26 cm. Contents: 1. Design and Implementation of High-Throughput Screening Assays / Ricardo Macarron and Robert P. Hertzberg Creation of a Small High-Throughput Screening Facility / Tod Flak Informatics in Compound Library . HT & PHENOTYPIC SCREENING THE MOLECULAR HAYSTACK Take control of your molecular haystack and find meaningful associations faster and with less hands-on time. With high-throughput screening (HTS) and phenotypic screening, you can tailor your process and find more meaningful matches in even the deepest haystacks. PHENOTYPIC SCREENINGFile Size: 6MB.


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High throughput screening Download PDF EPUB FB2

Explores the benefits and limitations of the latest high-throughput screening methods. With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity.

Moreover, it enables them to comply with the latest. High-throughput screening (HTS) is a method of scientific experimentation that comprises the screening of large compound libraries for activity against biological targets via the use of automation, miniaturized assays, and large-scale data analysis.

From: Handbook on the Toxicology of Metals (Fourth Edition), Download as PDF. About this page. Bioactive Screening Libraries are ready-to-use chemical libraries used for drug discovery, lab drug screening, drug target identification, and other pharmaceutical-related applications.

They are available for high- throughput screening (HTS) and high-content screening (HCS). The libraries consist of over 4, small molecules with validated biological and pharmacological activities.

The high-throughput methods High throughput screening book formulation screening are discussed specifically in the context of stress simulations and storage conditions. The case studies for modality-specific formulation development and the methods to predict long-term stability are also presented.

This third edition volume expands on the previous editions both by presenting more detailed protocols for the techniques described in the first and second editions of High Throughput Screening: Methods and Protocols and by covering important new procedures.

The first chapter of this book provides an overview of important assay development techniques, while the rest of.

In High Throughput Screening: Methods and Protocols, Second Edition, experts in the field fully update the previous edition to best serve as an introduction to HTS for scientists who are just entering the field, and as a provider of key, significant detail so as to be useful to scientists in established HTS operations.

Featuring new screening. Data Analysis Approaches in High Throughput Screening. By Asli N. Goktug, Sergio C. Chai and Taosheng Chen. Submitted: May 4th Reviewed: August 20th Published: January 23rd DOI: /Cited by: About this book Introduction In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically.

This concise, self-contained, and cohesive book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening (HTS) experiments from a statistically sound by: Assay Validation in High Throughput Screening – from Concept to Application.

By Sergio C. Chai, Asli N. Goktug and Taosheng Chen. Submitted: May 26th Reviewed: October 28th Published: June 3rd DOI: /Cited by: 1. news Screen compounds identifies six potential COVID therapeutics. 17 April | By Hannah Balfour (Drug Target Review). High-throughput screening of thousands of compounds has revealed several candidates, including lead compound ebselen, with the potential for treating COVID High-Throughput Screening Methods in Toxicity Testing - Kindle edition by Steinberg, Pablo.

Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading High-Throughput Screening Methods in Toxicity Testing/5(2). High throughput screening system is reviewed primely in this article, with emphasis on factors such as acting targets, suitability of assay methods to various targets, major parameters and Author: Hanspeter Gubler.

Each chapter is devoted to a major topic - high-throughput experimentation methodologies, integrated combinatorial synthesis and screening workflow, and applications to chemical catalysts with an emphasis on heterogeneous catalysis, olefin polymerization and. Applications that focus on developing novel high throughput screens for small molecule hits and immunotherapeutics may be assigned to ZRG1 BST-F (55).

• There are shared interests with Drug Discovery and Molecular Pharmacology (DMP) in the area of cancer drug discovery. Applications that focus on identifying cancer targets, molecular.

High-Throughput Screening: ROTOR HDA. Genome-wide screening is easy when you have the right tools. Reagent sets such as deletion mutant collections and the complete set of cloned yeast genes can be utilised for high-throughput 2-hybrid, synthetic genetic array, phenotypic and chemical-genetic analyses.

Book an Online Demo. High Throughput Screening (HTS) is a widely used drug discovery method that utilizes laboratory automation to gather a tremendously huge quantity of experimental data in a Author: Amancio Carnero.

High Throughput Screening: Methods, Techniques and Applications provides readers with an outline of key elements in the areas of assay development, detailed descriptions of a range of both biochemical and cell-based screening methodologies and strategies, as well as highlighting important steps in data analysis.

Summary Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high throughput screening (HTS).

High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how.

Explores the benefits and limitations of the latest high-throughput screening methods With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity.

Moreover, it enables them to comply with the latest Author: Pablo Steinberg. High-throughput screening or HTS is a hit identification method for scientific experimentation that is part of a continually evolving toolbox for the discovery of pharmaceutical start points.

HTS is a very successful strategy that forms an essential foundation of drug discovery and is especially relevant to the fields of biology and chemistry.Join us from 16–18 April in Durham, North Carolina, to learn about the state of the science of high-throughput toxicology and be equipped with the background to critically evaluate how it could be employed in a broad range of environmental risk assessment scenarios.